PNA-Driven Remote Actuation of DNA Nanospring Strain Sensors

reportActive / Technical Report | Accesssion Number: AD1230188 | Open PDF

Abstract:

The Year 4 extension of this project allowed us to investigate the actuation of novel gPNA-based nanofibers and characterization of 3D lever system. This 4th year extension has the following four subaims: (1) First demonstration of nanoscale Oriceps sensor; (2) Create design tool for oriceps by mapping the design space;(3) Explore actuatable PNA systems and attach oriceps; (4) Use oriceps to measure sub 2nm or greater than 8nm separations.

Author(s):
Taylor, Rebecca
Author Organization(s):
CARNEGIE-MELLON UNIV PITTSBURGH PA
Funding Organization(s):
AIR FORCE OFFICE OF SCIENTIFIC RESEARCH ARLINGTON VA, ARLINGTON, VA
Document Type:
Technical Report/Final Report
Publication Date:
2023 Mar 13
Pagination:
51

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DOCUMENT & CONTEXTUAL SUMMARY

Distribution Code:
A - Approved For Public Release
Distribution Statement: Public Release.
Copyright: Not Copyrighted

RECORD

Collection: TRECMS
Subject Terms
Keyword(s):
pna(peptide nucleic acids), PNA-Driven Remote Actuation, dna(DEOXYRIBONUCLEIC ACIDS), DNA Nanospring Strain Sensors, gPNA-based nanofibers, gpna(guanadine based pna), 3d(THREE DIMENSIONAL), 3d lever systems, nanoscale Oriceps sensors, design space mapping, actuatable PNA systems, fret(Forster resonance energy transfer), pna-based nanostructures
Subject Categories:
Biological and Medical Sciences; Biological and Medical Sciences
Creation Date:
2024 Jun 24
Update Date:
2024 Jun 27