Assessment of Clonal Hematopoiesis and Its Relationship to Cardiovascular Disease in Hodgkin Lymphoma Survivors

The funded project is proceeding forward without major difficulty. The proposal was approved by the Children's Oncology Group (COG), the DCP, and CIRB approval was obtained on. The study encompassing this research project (ALTE21C1) was activated within COG and COG member centers within the US have both agreed to participate and have proceeded with steps to activate the study at their institution . A webpage within the COG website has been constructed which contains the CIRB approved protocol and other resources to provide guidance, and answer questions for the participating centers. The workflows for certification of imaging centers for the cardiac MRI's has been launched and two centers have already been certified. The workflows for blood sample acquisition for clonal hematopoiesis have been defined and is ready to be executed once enrolled patients have begun participation in the study The committee members for the protocol meet monthly to address emerging issues, to enhance workflows and recruitment strategies. To date, there have been no major obstacles or delays in advancing this project toward its desired outcome.