Internal Standard and Deuterated Solvent Selection: A Crucial Step in PFAS- Based Fluorine-19 (19F) NMR Research

reportActive / Technical Report | Accesssion Number: AD1215045 | DOI: 10.21079/11681/47899 | Open PDF

Abstract:

This work is vital because it provides researchers with a framework and rationale for selecting the best internal standard and deuterated solvent for their nuclear magnetic resonance (NMR) analysis of per- and polyfluoroalkyl substances (PFAS)-based compounds. Selecting the best internal standard and deuterated solvent will help to ensure that their results are accurate, precise, and sensitive. The internal standard that is chosen can significantly affect the accuracy, precision, sensitivity, and quantification of NMR measurements. Therefore, it is essential to carefully select an internal standard and a matching deuterated solvent that are well-suited for analyzing PFAS compounds.

Author(s):
Fernando, P. U. ; Sullivan, Samantha N. ; Martinez-guerra, Edith ; Cobb, Jared S.
Author Organization(s):
ENGINEER RESEARCH AND DEVELOPMENT CENTER VICKSBURG MS
Funding Organization(s):
ARMY CORPS OF ENGINEERS WASHINGTON DC, WASHINGTON, DC
Document Type:
Technical Report/Technical Note
Publication Date:
2023 Nov 01
Pagination:
17

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution Code:
A - Approved For Public Release
Distribution Statement: Public Release.
Copyright: Not Copyrighted

RECORD

Collection: TRECMS
Subject Terms
Descriptor(s):
chemistry, chemical synthesis, magnetic resonance, nuclear magnetic resonance, resonance, acetic acid, acetonitrile, aqueous solutions, nitriles, organic chemistry, organic compounds, spectroscopy, standards, accuracy, acquisition, aromatic compounds, chemical shifts
Keyword(s):
nmr(nuclear magnetic resonance), pfas(per and polyfluoroalkyl substances)
Subject Categories:
Physics
Communities of Interest:
Descriptor(s):
chemistry, magnetic resonance, nuclear magnetic resonance, chemical synthesis, resonance, accuracy, aqueous solutions, spectroscopy, standards, acetic acid, acetonitrile, acquisition, chemical shifts, fluorine, measurement, nitriles, spectra
Creation Date:
2023 Nov 20
Update Date:
2023 Nov 28