Toward a Unified Multiscale Computational Model of the Human Body's Immediate Responses to Blast-Related Trauma: Proceedings and Expert Findings from a U.S. Department of Defense International State-of-the-Science Meeting

This document represents the complete proceedings of the tenth U.S. Department of Defense (DoD) International State-of-the-Science Meeting (SoSM) on Blast Injury Research, held August 1617, 2022, at the Arlington, Virginia, office of the RAND Corporation. The topic of the tenth SoSM was Toward a Unified Multiscale Computational Model of the Human Body's Immediate Responses to Blast-Related Trauma. The proceedings and findings from the meeting were intended to help address these objectives: 1. assess the state of the science of unified multiscale modeling of the human body's responses to blast exposure 2. identify major barriers and knowledge gaps impeding progress in the field, along with opportunities for investment in future research 3. identify additional opportunities for collaborative action (both government and public/private) that could accelerate progress 4. provide recommendations to advance preclinical and clinical research, determine key policy gaps, and identify areas to advance production development.