Imaging How a Neuron Computes

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Abstract:

During this MURI, the eleven laboratories have developed new imaging methodologies aimed at the scientific goal of understanding how neurons compute with great success. In particular, we have had major publications in the stimulated Raman scattering (Wei and Yuste), methods for methods for demixing spatiotemporal calcium imaging data (Paninski) and their application to multiplane imaging in vivo (Yuste) and sesrial EM studies (Lichtman). We also have continued to develop nanodiamond voltage sensing, atomic force microscopy and SPAD. It is fair to say that this MURI has pioneered, more than any other group, the development of Neurotechnology in the US.

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