Blood Substitute and Method of Making.

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Abstract:

This invention relates to blood substitutes, and methods for their preparation. More particularly, it relates to a novel composition which can be administered to human patients as a blood substitute by transfusion. Hemoglobin-containing vesicles suitable for use as red blood cell substitutes in artificial blood are prepared by extruding a suspension of hemoglobin, a saturated neutral lipid, a sterol, and optionally, a charged lipid through a filter of suitable pore size.

Author(s):
Gaber, Bruce P. ; Yager, Paul ; Sheridan, James P. ; Chang, Eddie L.
Author Organization(s):
DEPARTMENT OF THE NAVY WASHINGTON DC
Descriptive Note:
Patent Application,
Pagination:
0016

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release
Distribution Statement:
Availability: This Government-owned Invention Available For U.s. Licensing And, Possibly, For Foreign Licensing. Copy Of Application Available Ntis.

RECORD

Collection: TR
Identifying Numbers
Report Number(s):
PAT-APPL-508 692
 Subject Terms
Communities of Interest:
No COI(s) Identified
Descriptor(s):
*Patent applications, *Blood substitutes, Hemoglobin, Lipids, Mixtures, Neutral
Field(s)/Group(s):
Medicine and Medical Research
Report Date:
1983 Jun 28