Characterization of Nanoparticles by Capillary Electrophoresis and Trapping of Nanoparticles in Microfluidics Device

reportActive / Technical Report | Accession Number: ADA609248 | Open PDF

Abstract:

The contractor report describes research performed for Contract No. W7702-04R-021. The work was carried out in support of CRTI 03-005RD. The report describes the use of capillary electrophoresis CE as an analytical method for characterizing gold, polymer and iron oxide nanoparticles NPs. The analyte species were detected by UVvis or laser-induced fluorescence LIF spectroscopy. For analytes that possessed neither UVvis absorbance nor LIF, indirect methods of detection were employed whereby a signal-generating molecular species was added to the running buffer. NPs from a variety of commercial sources and from custom syntheses were studied. The report demonstrates that CE is a valuable tool in NP research. The report also demonstrates the feasibility of trapping nanoparticles in microfluidic devices for sample clean up and detection.

Author(s):
Tang, T. ; Jemere, A. B. ; Mah, D. C. ; Lee, W. E.
Author Organization(s):
CANADA WEST BIOSCIENCES CALGARY (ALBERTA)
Descriptive Note:
Contract rept.
Pagination:
0034

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release
Distribution Statement:
Approved For Public Release; Distribution Is Unlimited.

RECORD

Collection: TR
Identifying Numbers
Report Number(s):
DRDC-S-CR-2009-177
Contract/Grant Number(s):
W7702-04R-021
Project Number(s):
03-0005RD
Monitor Series:
CR-2009-177, DRDC-S
 Subject Terms
Joint Capability Areas:
JCA_5_Command and Control; JCA_5.3_Planning; JCA_1.2.7_Experimentation
Communities of Interest:
Biomedical
Descriptor(s):
*ELECTROPHORESIS, *FLUIDICS, *LASER INDUCED FLUORESCENCE, *NANOPARTICLES, *TRAPPING(CHARGED PARTICLES), GOLD, IRON OXIDES, POLYMERS, SPECTROSCOPY
Field(s)/Group(s):
Physical Chemistry, Radiation and Nuclear Chemistry, Fluidics and Fluerics, Electricity and Magnetism
Keyword(s):
CE(CAPILLARY ELECTROPHORESIS), FOREIGN REPORTS, LIFS(LASER INDUCED FLUORESCENCE SPECTROSCOPY), MICROFLUDICS, REAGENTS
Report Date:
2009 Aug 01
Creation Date:
2014 Nov 03