Early Detection of Heterotopic Ossification for Effective Prevention and Treatment

reportActive / Technical Report | Accession Number: ADA600600 | Open PDF

Abstract:

Heterotopic ossification HO is a pathological condition where soft tissues, such as muscles, calcify. Clinically, there are several forms of HO. Relevant to orthopaedic traumatology is HO that occurs in elbow and hip as a complication of injury, burn, brain injury or surgery. The prevalence of HO in wartime extremity injuries, particularly after amputation, is as high as 64. HO can be painful and impair the motions and functions of prostheses and the affected extremities. Prophylactic radiation and medications such as nonsteroidal anti-inflammatory drugs NSAIDs are effective, but these measures are not without serious side-effects and may be impractical for wartime injuries.

Author(s):
Zhang, Zijun
Author Organization(s):
MEDSTAR RESEARCH INST HYATTSVILLE MD
Descriptive Note:
Final rept. 30 Sep 2010-28 Jan 2014
Supplementary Note:
The original document contains color images. DOI: 10.21236/ADA600600
Pagination:
0016

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release
Distribution Statement:
Approved For Public Release; Distribution Is Unlimited.

RECORD

Collection: TR
Identifying Numbers
Contract/Grant Number(s):
W81XWH-10-1-0982
Monitor Series:
USAMRMC
 Subject Terms
Joint Capability Areas:
JCA_2.2.2_Imagery Collection; JCA_2.2_Collection; JCA_5_Command and Control; JCA_1.3.2_Personnel Management; JCA_5.5.2_Task; JCA_5.5_Direct; JCA_1.2.3_Educating; JCA_1.2.5_Lessons Learned; JCA_4.3_Maintain; JCA_5.3_Planning
Communities of Interest:
No COI(s) Identified
Descriptor(s):
*BONES, *MUSCULOSKELETAL DISEASES, AMPUTATION, BRAIN, DETECTION, DRUGS, EXTREMITIES, HIP, MOTION, PREVENTIVE MEDICINE, PROSTHETICS, SOFT TISSUES, WOUNDS AND INJURIES
Field(s)/Group(s):
Anatomy and Physiology, Medicine and Medical Research
Report Date:
2014 Apr 01
Creation Date:
2014 Jun 16