Microsporidiosis

reportActive / Technical Report | Accession Number: ADA547526 | Open PDF

Abstract:

Definition Microsporidiosis is infection by eukaryotic unicellular protists of the phylum Microsporidia. They are considered most closely related to the fungi, but customarily are discussed among the protozoa. Several genera of microsporidia have been identified in human infections Nosema, Brachiola, Vittaforma, Pleistophora, Trachipleistophora, Enterocytozoon, Encephalitozoon, Septata, and Anncaliia All microsporidia are obligate intracellular parasites, but pathologic changes vary with genus and species. In humans, infection may be latent or subclinical until the immune system is suppressed. Microsporidia are a significant opportunistic pathogen in patients with AIDS. Clinical features vary with the location and extent of infection. Microsporidia may infect virtually any tissue or organ of the body, including muscle, intestine, gallbladder, liver, kidneys, eyes, brain, lungs, skin, and nasal sinuses. Intestinal microsporidiosis is most common, occurring in 30 to 50 of AIDS patients with chronic diarrhea. Untreated intestinal, renal, cerebral, hepatic and disseminated infections are usually fatal.

Author(s):
Cali, Ann ; Neafie, Ronald C. ; Takvorian, Peter M.
Author Organization(s):
RUTGERS - THE STATE UNIV NEWARK NJ
Supplementary Note:
See also ADA545141. Chapter 14 from e-book, Topics on the Pathology of Protozoan and Invasive Arthropod Diseases.
Pagination:
0025

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release
Distribution Statement:
Approved For Public Release; Distribution Is Unlimited.

RECORD

Collection: TR
Identifying Numbers
Monitor Series:
AFIP
 Subject Terms
Modernization Areas:
Directed Energy
Communities of Interest:
No COI(s) Identified
Descriptor(s):
*INFECTIOUS DISEASES, *PATHOLOGY, *PROTOZOA, ACQUIRED IMMUNE DEFICIENCY SYNDROME, BRAIN, CELLS(BIOLOGY), CLINICAL MEDICINE, DIARRHEA, EYE, FUNGI, GALLBLADDER, INTESTINES, KIDNEYS, LIVER, LUNG, ORGANS(ANATOMY), PARANASAL SINUSES, PARASITES, PATIENTS, SPORES
Field(s)/Group(s):
Medicine and Medical Research
Keyword(s):
*MICROSPORIDIOSIS, NOSEMA, BRACHIOLA, VITTAFORMA, PLEISTOPHORA, TRACHIPLEISTOPHORA, ENTEROCYTOZOON, ENCEPHALITOZOON, SEPTATA, ANNCALIIA, EUKARYOTIC, PHYHLUM
Report Date:
2011 Jun 01
Creation Date:
2011 Sep 14