Comprehensive 3D Model of Shock Wave-Brain Interactions in Blast-Induced Traumatic Brain Injuries

reportActive / Technical Report | Accession Number: ADA521780 | Open PDF

Abstract:

This project aims at the development of a realistic and accurate numerical model that can capture the essential physics of shock wave propagation and its interaction with the skull and brain tissue. This information would enable us to address and study the diverse mechanisms damaging the brain to better understand causes and effects during blast-induced traumatic brain injuries. At the present time, a fully 3D numerical model on fixed computational grids for nonlinear acoustic and elastic propagation has been developed and validated against published work and in-house experiments. A realistic modeling domain based on the segmentation and 3D reconstruction of sequential anatomical data obtained from the Visual Human Project is used as input to the computational kernel. Adaptive grid versions of the algorithms by means of wavelet and radial basis functions approaches as well as the inclusion of cavitation effects via effective medium theory and a graphical user interface to the simulation software are currently under development.

Author(s):
Curra, Francesco
Author Organization(s):
WASHINGTON UNIV SEATTLE
Descriptive Note:
Annual progress rept. 8 Sep 2008-2009
Supplementary Note:
The original document contains color images.
Pagination:
0009

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release
Distribution Statement:
Approved For Public Release; Distribution Is Unlimited.

RECORD

Collection: TR
Identifying Numbers
Contract/Grant Number(s):
W81XWH-08-1-0520
Monitor Series:
USAMRMC
 Subject Terms
Joint Capability Areas:
JCA_5_Command and Control; JCA_5.5_Direct; JCA_3.2_Engagement; JCA_3_Force Application; JCA_3.2.1_Kinetic Means; JCA_5.5.1_Communicate Intent and Guidance; JCA_5.5.2_Task; JCA_1_Force Support; JCA_1.3_Human Capital Management; JCA_1.3.2_Personnel Management; JCA_1.4.2_Health Service Delivery; JCA_1.4_Force Support; JCA_1.2.7_Experimentation; JCA_6_Net Centric; JCA_8_Building Partnerships
Modernization Areas:
Quantum Science and Computing
Communities of Interest:
Biomedical
Descriptor(s):
*TRAUMATIC SHOCK, *GRAPHICAL USER INTERFACE, COMPUTERIZED SIMULATION, VALIDATION, ACCURACY, ELASTIC WAVES, CAVITATION, SKULL, ALGORITHMS, COMPUTER PROGRAMS, WAVE PROPAGATION
Field(s)/Group(s):
Operations Research, Computer Programming and Software, Medicine and Medical Research
Keyword(s):
*VHP(VISUAL HUMAN PROJECT), *TRAUMATIC BRAIN INJURIES, NONLINEAR WAVEFORMS
Report Date:
2009 Oct 01
Creation Date:
2010 Jun 23