Capillary Inlet Concentrator for the Integrated Virus Detection System (IVDS)

reportActive / Technical Report | Accession Number: ADA516728 | Open PDF

Abstract:

The standard method for concentration of virus samples with the Integrated Vims Detection System IVDS is to use a tangential flow filtration system to reduce the volume of the sample, while removing impurities such as salts and small cellular debris. This report investigated the IVDS ability to concentrate the virus sample as well as remove impurities with a filtration attachment on the inlet side of the electrospray module. The filtration attachment or concentrator allowed the virus sample to be purified and concentrated and then analyzed with the IVDS without removing the sample from the IVDS.

Author(s):
Wick, Charles H. ; Mccubbin, Patrick E.
Author Organization(s):
EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD RESEARCH AND TECHNOLOGY DIR
Descriptive Note:
Final rept. Oct 2004-Jul 2005
Supplementary Note:
Prepared in collaboration with Optimetrics, Inc., Abingdon, MD. The original document contains color images. All DTIC reproductions will be in black and white.
Pagination:
0012

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release
Distribution Statement:
Approved For Public Release; Distribution Is Unlimited.

RECORD

Collection: TR
Identifying Numbers
Report Number(s):
ECBC-TR-750
Monitor Series:
ECBC/RTD
 Subject Terms
Joint Capability Areas:
JCA_6_Net Centric; JCA_6.4.1_Secure Information Exchange; JCA_3.2_Engagement; JCA_3_Force Application; JCA_3.2.2_Non-Kinetic Means; JCA_6.4_Information Assurance; JCA_5_Command and Control; JCA_5.3_Planning; JCA_6.2.1_Information Sharing; JCA_6.2.2_Computing Services; JCA_6.2.3_Core Enterprise Services; JCA_8_Building Partnerships
Communities of Interest:
Counter WMD
Descriptor(s):
*DETECTION, *VIRUSES, BIOLOGICAL AGENTS, DEBRIS, CELLS, FILTRATION, PARTICLES, CONCENTRATION(COMPOSITION), INLETS, CAPILLARITY, CONDENSATION, MOBILITY, INJECTION, IMPURITIES
Field(s)/Group(s):
Microbiology, Chemical, Biological and Radiological Warfare
Keyword(s):
IVDS(INTEGRATED VIRUS DETECTION SYSTEM), DIFFERENTIAL MOBILITY ANALYZER, VIRUS CONCENTRATION, VIRUS FILTRATION, CONDENSATION PARTICLE COUNTER, MS 2, ELECTROSPRAY INJECTION
Report Date:
2010 Mar 01
Creation Date:
2010 Apr 07