Treatment of Hantavirus Pulmonary Syndrome

reportActive / Technical Report | Accession Number: ADA486103 | Open PDF

Abstract:

Viruses in the genus Hantavirus can cause one of two illnesses when transmitted from rodents to humans hemorrhagic fever with renal syndrome HFRS or hantavirus pulmonary syndrome HPS. Of the two diseases, HPS is more severe with an approximate 40 mortality across the Americas. The high rate of mortality could be reduced if effective therapeutics could be discovered for treatment of this illness. Herein we review approaches being explored for the discovery of therapeutics for HPS and how they could be employed in treatment and prevention of disease.

Author(s):
Jonsson, Colleen B. ; Hooper, Jay ; Mertz, Gregory
Author Organization(s):
ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FORT DETRICK MD
Descriptive Note:
Journal article
Supplementary Note:
Published in Antiviral Research, v78 p162-169, 2008. The original document contains color images.
Pagination:
0009

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release
Distribution Statement:
Approved For Public Release; Distribution Is Unlimited.

RECORD

Collection: TR
Identifying Numbers
Monitor Series:
USAMRIID
 Subject Terms
Joint Capability Areas:
JCA_7.2.1_Mitigate Lethal Effects; JCA_7.2_Mitigate; JCA_7_Protection; JCA_5_Command and Control; JCA_5.3_Planning
Communities of Interest:
No COI(s) Identified
Descriptor(s):
*VIRUS DISEASES, *THERAPY, IMMUNOTHERAPY, VIRUSES, VACCINES, LUNG, REPRINTS, ANTIVIRAL AGENTS
Field(s)/Group(s):
Medicine and Medical Research
Keyword(s):
*HANTAVIRUSES, *HPS(HANTAVIRUS PULMONARY SYNDROME), BUNYAVIRUS, ANTIVIRAL THERAPY, RIBAVIRIN, HFRS(HEMORRHAGIC FEVER WITH RENAL SYNDROME)
Report Date:
2007 Oct 14
Creation Date:
2008 Sep 24