Development of Microdevices for Biomolecular Detection

reportActive / Technical Report | Accession Number: ADA484233 | Open PDF

Abstract:

Biosensors suitable for providing informed rapid treatment analysis for soldiers and real-time environmental monitoring of toxic agents were developed. In particular, glass encapsulated field-effect sensors that are chemically robust and batch-fabricated by a conventional 6 wafer process were developed and demonstrated for the following applications i Polymerase Chain Reaction PCR product quantification, ii Integrated microelectronic device for label-free nucleic acid amplification and detection, and iii Monitoring of heparin and its low molecular weight analogs.

Author(s):
Manalis, Scott R.
Author Organization(s):
MASSACHUSETTS INST OF TECH CAMBRIDGE
Descriptive Note:
Final rept. 1 Feb 2004-31 Dec 2007
Supplementary Note:
The original document contains color images. DOI: 10.21236/ADA484233
Pagination:
0007

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release
Distribution Statement:
Approved For Public Release; Distribution Is Unlimited.

RECORD

Collection: TR
Identifying Numbers
Report Number(s):
AFRL-SR-AR-TR-08-0340
Contract/Grant Number(s):
FA9550-04-1-0049
Monitor Series:
TR-08-0340, AFOSR
 Subject Terms
Joint Capability Areas:
JCA_6_Net Centric; JCA_1.4_Force Support; JCA_5_Command and Control
Modernization Areas:
Biotechnology
Communities of Interest:
Materials and Manufacturing Processes
Descriptor(s):
*TOXIC AGENTS, *BIOMOLECULES, *BIOLOGICAL DETECTION, *MICROELECTRONICS, CHAIN REACTIONS, HEPARIN, NUCLEIC ACIDS, SILICON, POLYMERIZATION, REAL TIME, MONITORING
Field(s)/Group(s):
Chemical, Biological and Radiological Warfare
Keyword(s):
*MICRODEVICES, *BIOSENSORS, SILICON FIELD EFFECT, PCR(POLYMERASE CHAIN REACTION)
Report Date:
2008 Jun 01
Creation Date:
2008 Aug 13