A Phase 1/2 Trial of a Tetravalent Live-Attenuated Dengue Vaccine in Flavivirus-Naive Thai Infants

reportActive / Technical Report | Accession Number: ADA481707 | Open PDF

Abstract:

The Walter Reed Army Institute of Research WRAIR has produced a tetravalent live-attenuated dengue vaccine that has been well tolerated and immunogenic in U.S. adults and Thai children. As infants are considered by many as an important age group for vaccination in dengue-endemic countries, we evaluated the vaccine in Thai flavivirus-na ve infants who are at risk for dengue.

Author(s):
Watanaveeradej, V. ; Kerdpanich, A. ; Samakoses, R. ; Tanakijaru, K. ; Aree, C. ; Simasathien, S. ; Mammen, M. P. ; Nisalak, A. ; Hengprasert, S. ; Jarman, R. J. ; Gibbons, R. V. ; Innis, B. L. ; Hutagalung, Y. ; Chunsuttiwat, S. ; Sun, W. ; Endy, T. P. ; Thomas, S. ; Eckels, K. H. ; Putnak, R. ; Vaughn, D. W.
Author Organization(s):
PHRAMONGKUTKLAO HOSPITAL BANGKOK (THAILAND)
Descriptive Note:
Conference paper
Supplementary Note:
See also ADM002075., The original document contains color images. Presented at the Army Science Conference (25th) held in Orlando, FL on 27-30 November 2006.
Pagination:
0006

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release
Distribution Statement:
Approved For Public Release; Distribution Is Unlimited.

RECORD

Collection: TR
Identifying Numbers
Monitor Series:
WRAIR
 Subject Terms
Joint Capability Areas:
JCA_1.4_Force Support; JCA_6_Net Centric; JCA_3.2_Engagement; JCA_3_Force Application; JCA_6.4.1_Secure Information Exchange; JCA_1.4.2_Health Service Delivery; JCA_3.2.2_Non-Kinetic Means; JCA_6.4_Information Assurance; JCA_1.4.1_Force Health Protection; JCA_1_Force Support; JCA_5_Command and Control; JCA_5.3_Planning; JCA_1.3_Human Capital Management; JCA_1.3.1_Personnel and Family Support; JCA_8_Building Partnerships
Modernization Areas:
Biotechnology
Communities of Interest:
No COI(s) Identified
Descriptor(s):
*VACCINES, *INFANTS, DENGUE, IMMUNIZATION, THAILAND
Field(s)/Group(s):
Medicine and Medical Research, Pharmacology
Keyword(s):
FOREIGN REPORTS, FLAVIVIRUS NAIVE
Report Date:
2006 Nov 01
Creation Date:
2008 Jun 11