Generation, Sampling, and Analysis for Low-Level GF (Cyclo-Sarin) Vapor for Inhalation Toxicology Studies

reportActive / Technical Report | Accession Number: ADA456893 | Open PDF

Abstract:

The generation, sampling, and analysis system used for low-level GB inhalation studies was modified to test the nerve agent GF. A saturator cell used in conjunction with an inhalation chamber generated low level OF vapor at concentrations ranging from 0.004 - 0.05 mgcu m. Additional testing with a syringe drive spray atomization system generated OF vapor concentrations from 0.7 - 2 mgcu m. This capability was important to determine sub-lethal effects primarily meioses for inhalation toxicology studies. In addition, the techniques successfully employed for this study would lay the foundation for testing low-level VX.

Author(s):
Muse, Jr., William T. ; Thomson, Sandra A. ; Crouse, Charles L. ; Matson, Kathy L.
Author Organization(s):
EDGEWOOD CHEMICAL BIOLOGICAL CENTER ABERDEEN PROVING GROUND MD
Descriptive Note:
Final rept. Apr 2002-Apr 2005
Supplementary Note:
Prepared in collaboration with GEO-CENTERS, Inc., part of Science Applications International Corp.
Pagination:
0021

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release
Distribution Statement:
Approved For Public Release; Distribution Is Unlimited.

RECORD

Collection: TR
Identifying Numbers
Report Number(s):
ECBC-TR-499
Project Number(s):
201400
Monitor Series:
ECBC
 Subject Terms
Joint Capability Areas:
JCA_5_Command and Control; JCA_5.3_Planning; JCA_3.2_Engagement; JCA_3_Force Application; JCA_6_Net Centric; JCA_6.1.3_Switching and Routing; JCA_3.2.2_Non-Kinetic Means; JCA_6.4.1_Secure Information Exchange; JCA_3.2.1_Kinetic Means; JCA_6.1_Information Transport; JCA_6.2.1_Information Sharing; JCA_6.2.2_Computing Services; JCA_6.2.3_Core Enterprise Services; JCA_8_Building Partnerships
Communities of Interest:
No COI(s) Identified
Descriptor(s):
*SAMPLING, *LOW LEVEL, *NERVE AGENTS, *INHALATION, *TOXICOLOGY, VAPORS, SUBLETHAL DOSAGE, MEIOSIS, ATOMIZATION, GB AGENT, CONCENTRATION(COMPOSITION), CHEMICAL AGENTS, SATURATION
Field(s)/Group(s):
Anatomy and Physiology, Toxicology, Chemical, Biological and Radiological Warfare
Keyword(s):
*INHALATION TOXICOLOGY, *AGENT GENERATION, CYCLOHEXYL METHYLPHOSPHONOFLUORIDATE, GF(CYCLO SARIN), SATURATOR CELLS, SPRAY ATOMIZATION, SARIN, VX
Report Date:
2006 Oct 01
Creation Date:
2006 Nov 22