The Safety of Desiccated Baralyme(TM) in the Narkomed-M Anesthesia Machine: The Effect of Isoflurane and Sevoflurane at Low and High Flow O2 on Absorbent Temperature

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Abstract:

Objective To determine the clinical safety of using partially desiccated BaralymeTM in a Narkomed-M anesthesia machine by measuring the maximum temperature within the absorbent and time to maximum temperature under standard OR conditions. Methods Four experimental conditions were set using sevoflurane experiment vs. isoflurane control at low 3L vs. high 5L O2 flows. Baralyme was partially desiccated by 12 hours high-flow air to 10.8 moisture. Results Twenty three trials showed no significant interaction of Agent and Liter-flow for temperature p.896 or time p.668, nor was there a significant main effect for Agent for temperature p.230 or time p.863. Three Liter-flow showed a consistently higher temperature than the 5L flow overall 44.5 degrees C vs. 41.5 degrees C, p.001, and for both Isoflurane, 44.8 degrees C vs. 41.8 degrees C, p.001 and Sevoflurane, 44.2 degrees C vs. 41.1 degrees C, p.006. Conclusion Partially desiccated Baralyme showed no clinically significant temperature increases and appears to be safe to use in a Narkomed-M under normal clinical conditions.

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