Ventilation-Perfusion Alterations after Inhalation Injury in an Ovine Model

reportActive / Technical Report | Accession Number: ADA383517 | Open PDF

Abstract:

Ventilation- perfusion alterations after smoke inhalation injury in an ovine model. J. Appl. PhysioL. 815 A 2250-2259, 1996. To study the pathophysiological mechanism of progressive hypoxemia after smoke inhalation injury, alterations in ventilation-perfusion ratio VAQ were studied in an ovine model by using the multiple inert gas elimination technique. Because ethane was detected in expired gas of some sheep, we replaced ethane with krypton, which was a unique application of the multiple inert gas elimination technique when one of the experimental gases is present in the inspirate. Severity-related changes were studied 24 h after injury in control and mild, moderate, and severe inhalation injury groups.

Author(s):
Shimazu, Takeshi ; Yukioka, Tetsuo ; Ikeuchi, Hisashi ; Mason, Arthur D., Jr. ; Wagner, Peter D.
Author Organization(s):
ARMY INST OF SURGICAL RESEARCH FORT SAMHOUSTON TX
Descriptive Note:
Final rept.,
Supplementary Note:
Pub. in Jnl. of Applied Physiology, v81 n5, p2250-2259, 1996.
Annotation:
Reprint: Ventilation-Perfusion Alterations after Inhalation Injury in an Ovine Model
Pagination:
0011

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release

RECORD

Collection: TR
Identifying Numbers
Project Number(s):
3A16110A91C
Monitor Series:
USAMRMC
 Subject Terms
Joint Capability Areas:
JCA_5_Command and Control; JCA_5.3_Planning; JCA_1_Force Support; JCA_1.2.5_Lessons Learned; JCA_8_Building Partnerships; JCA_1.4_Force Support; JCA_8.2_Shape; JCA_1.3_Human Capital Management; JCA_1.4.1_Force Health Protection; JCA_5.3.2_Apply Situational Understanding; JCA_1.2_Force Preparation; JCA_1.3.2_Personnel Management; JCA_6.4.1_Secure Information Exchange; JCA_1.2.3_Educating; JCA_8.2.1_Partner with Governments and Institutions; JCA_8.2.2_Provide Aid to Foreign Partners and Institutions
Communities of Interest:
No COI(s) Identified
Descriptor(s):
*VENTILATION, *SMOKE, *WOUNDS AND INJURIES, *INHALATION, GASES, HYPOXIA, PHYSIOLOGY, PATHOLOGY, ETHANES, SHEEP, KRYPTON
Field(s)/Group(s):
Anatomy and Physiology, Medicine and Medical Research, Air Conditioning, Heating, Lighting and Ventilating
Keyword(s):
*OVINE MODEL, LUNG INJURY, SEVERITY RELATED CHANGES, PE6110A
Report Date:
1996 May 01
Creation Date:
2000 Nov 15