New Therapeutic Approaches and Prognostic Assays for Breast Cancer: Radiolabeled Ligands and Antibodies and Quantitative PCR

reportActive / Technical Report | Accession Number: ADA378605 | Open PDF

Abstract:

Breast cancer is a tumor of the mammary gland epithelium affecting about 176,000 women in the western hemisphere and killing about 50,000 people every year in the United States. A substantial body of epidemiological, experimental, and clinical evidence indicates that exposure to the natural hormones, estrogen, progesterone and prolactin, which are important for the normal development and function of the breast tissue, play a major role in the growth of breast cancer cells and may even contribute to the development of breast cancer.

Author(s):
Poola, Indra
Author Organization(s):
HOWARD UNIV WASHINGTON DC
Descriptive Note:
Annual rept. 30 Sep 1997-29 Sep 1998
Supplementary Note:
DOI: 10.21236/ADA378605
Pagination:
0088

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release

RECORD

Collection: TR
Identifying Numbers
Contract/Grant Number(s):
DAMD17-94-J-4495
Monitor Series:
USAMRMC
 Subject Terms
Joint Capability Areas:
JCA_5_Command and Control; JCA_5.3_Planning; JCA_1.2.3_Educating; JCA_1.2.5_Lessons Learned
Communities of Interest:
No COI(s) Identified
Descriptor(s):
*ANTIBODIES, *BREAST CANCER, EPITHELIUM, HORMONES, TISSUES(BIOLOGY), LIGANDS, CELLS(BIOLOGY), LABELED SUBSTANCES, RADIOACTIVE ISOTOPES, MAMMARY GLANDS, PROGESTERONE, ESTROGENS, PROLACTIN
Field(s)/Group(s):
Biochemistry, Medicine and Medical Research
Keyword(s):
*PROGNOSTIC FACTORS, PCR (POLYMERASE CHAIN REACTIONS), RADIOLABELED LIGANDS
Report Date:
1998 Oct 01
Creation Date:
2000 Jul 05