Oral Bioavailability of TPH and Other Chemicals in Soil: Experimental Issues and Risk Assessment Applications.
Abstract:
Total Petroleum Hydrocarbon TPH contamination of soil is a problem at Air Force bases nationwide, causing it to be a major environmental clean-up concern. Human exposure to TPH in the soil can occur through several pathways, including ingestion of soil or sediment particles. Exposure through ingestion of TPH contaminated soils can be investigated using oral soil dosing studies. This technical report focuses on the methods used in soil dosing studies, the effects of soil on the bioavailability or toxicity of contaminants, and the potential use of bioavailability information in risk assessments and the development of risk-based clean-up sites.
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