New Therapeutic Approaches and Prognostic Assays for Breast Cancer: Radiolabeled Ligands and Antibodies and Quantitative PCR.

reportActive / Technical Report | Accession Number: ADA327015 | Open PDF

Abstract:

The specific aims of our proposal are to develop highly sensitive PCR methods for rapid, specific diagnosis of breast cancers on the basis of their estrogen and progesterone receptor expression. The results we have obtained indicate the feasibility of identifying and quantitating various forms of the hormone receptors in a small amount of tumor tissue by molecular assays.

Author(s):
Taylor, Robert
Author Organization(s):
HOWARD UNIV WASHINGTON DC
Descriptive Note:
Annual rept. 30 Sep 95-29 Sep 96,
Pagination:
0015

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release

RECORD

Collection: TR
Identifying Numbers
Contract/Grant Number(s):
DAMD17-94-J-4495
Monitor Series:
USAMRMC
 Subject Terms
Joint Capability Areas:
JCA_5_Command and Control; JCA_1.2.5_Lessons Learned
Modernization Areas:
Fully Networked C3
Communities of Interest:
Biomedical
Descriptor(s):
*ANTIBODIES, *LABELED SUBSTANCES, *BREAST CANCER, HORMONES, TISSUES(BIOLOGY), MOLECULES, NEOPLASMS, DEOXYRIBONUCLEIC ACIDS, DIAGNOSIS(MEDICINE), LIGANDS, RIBONUCLEIC ACIDS, PROGESTERONE, ESTROGENS
Field(s)/Group(s):
Biochemistry, Genetic Engineering and Molecular Biology, Anatomy and Physiology, Medicine and Medical Research
Keyword(s):
PCR(POLYMERASE CHAIN REACTIONS), MOLECULAR ASSAYS, RADIOLABELED LIGANDS
Report Date:
1996 Oct 01
Creation Date:
1997 Jul 23