Summary of Human Health Risk Assessment Guidelines and Methodologies.

This report presents an overview of risk assessment guidelines and methodologies for evaluating cancer and noncancer hazards due to exposure to environmental substances. An overview of the National Research Councils 1994 report Science and Judgment in Risk Assessment has been included. Although other federal agencies have established risk assessment guidelines, this report focuses on guidelines and methodologies currently in use or currently proposed by the U. S. Environmental Protection Agency. The primary purpose of this report is to identify key issues pertinent to cancer and noncancer risk assessments that impact the risk assessment process and result in more plausible risk estimates.