Live Fire Support Services Expansion of Ngas Model to Include Nitrogen Dioxide Effects in the Rat

reportActive / Technical Report | Accession Number: ADA283928 | Open PDF

Abstract:

The N-gas model is an empirical tool developed by the fire science community to predict toxic potency of various materials when burned based on the chemical nature of gases produced. This research is extending applicability of the N-gas equation to military scenarios by expanding the empirical formula to include the effects of exposure to NO2 in rodents. Rats are exposed, nose-only and under controlled conditions, to nitrogen dioxide, singly and in combination with carbon monoxide, carbon dioxide and air. LC50 values are determined based on 30 minute exposure, followed by 2 week post exposure. Blood gas, hemoglobin and respiratory data are collected.

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