Study of Nephropathia Epidemica (NE) in Sweden.

reportActive / Technical Report | Accession Number: ADA261711 | Open PDF

Abstract:

A total of 3524 rodents collected in a HFRS endemic area of Sweden were tested for Puumala PUU virus infection both viral antigen in lungs and specific antibodies in serum by ELISA. The material included 2493 Clethrionomys glareolus, 620 C. rufocanus, 367 Microtus agrestis, 39 Myopus Schisticolor and 5 Apodemus flavicollis. C. glareolus was found to be the most important vector of PUU virus. Infection rate did correlate with population density over time but with a time lag of one year. In addition monoclonal antibodies to PUU virus were generated and used for characterisation of virus and development of new diagnostic techniques. Two epidemiological studies, one in Bashkirtostan Russia and one among military personnel in Sweden were also performed. Sequele post HFRS in man were investigated.... Epidemiology, Immunology, BD, Foreign, RAD I.

Author(s):
Niklasson, Bo
Author Organization(s):
NATIONAL BACTERIOLOGICAL LAB STOCKHOLM (SWEDEN)
Descriptive Note:
Final rept. 15 Nov 88-14 Nov 91,
Supplementary Note:
DOI: 10.21236/ADA261711
Pagination:
0027

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release
Distribution Statement:
Approved For Public Release; Distribution Is Unlimited.

RECORD

Collection: TR
Identifying Numbers
Contract/Grant Number(s):
DAMD17-89-Z-9010
Task Number(s):
AB
Project Number(s):
3M162787A871
Monitor Series:
USAMRDC
 Subject Terms
Joint Capability Areas:
JCA_3.2_Engagement; JCA_3_Force Application; JCA_6.4.1_Secure Information Exchange; JCA_6_Net Centric; JCA_6.4_Information Assurance; JCA_3.2.2_Non-Kinetic Means; JCA_1.4.1_Force Health Protection; JCA_1.4_Force Support; JCA_5_Command and Control; JCA_1_Force Support; JCA_5.3_Planning
Modernization Areas:
Space
Communities of Interest:
No COI(s) Identified
Descriptor(s):
*HEMORRHAGIC FEVERS, *MEDICAL RESEARCH, *EPIDEMIOLOGY, *SWEDEN, USSR, DENSITY, MILITARY PERSONNEL, FOREIGN, RATES, VIRUS DISEASES, ANTIGENS, POPULATION, LUNG, ANTIBODIES, IMMUNOLOGY, MONOCLONAL ANTIBODIES, RODENTS
Field(s)/Group(s):
Medicine and Medical Research
Keyword(s):
NEPHROPATHIA EPIDEMICA, PUUMALA VIRUS INFECTIOUS, PE62787A, WU385, WUDA315683
Report Date:
1993 Jan 28