L-Tryptophan, Sleep, and Performance.

reportActive / Technical Report | Accession Number: ADA181941 | Open PDF

Abstract:

Planning for adequate rest and predicting the consequences of inadequate sleep or cumulative sleep loss should be an important consideration in mission logistics. The use of a sleeping aid may be appropriate to permit personnel to maximize sleep effectiveness in operational environments. At NHRC, we have investigated the amino acid l-tryptophan as a non sedating sleeping aid for military use. Attention focused on l-tryptophan because of its role as the dietary precursor of serotonin. the neurotransmitter first identified by Jouvet as involved in the regulation of sleep. Recent reviews continue to debate the effectiveness of 1-tryptophan as a sleeping aid and the underlying mechanism for its effects. Keywords Tryptophan, Performance, Reaction time, Sleep, Memory, Insomnia, Humans, Jet Lag, Arousal, Threshold.

Author(s):
Spinweber, Cheryl L.
Author Organization(s):
NAVAL HEALTH RESEARCH CENTER SAN DIEGO CA
Descriptive Note:
Interim rept.,
Supplementary Note:
Presented at the NATO Defense Research Group (DRG) Seminar, Lyon, France, 16-17 Mar 87.
Pagination:
0025

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release

RECORD

Collection: TR
Identifying Numbers
Report Number(s):
NHRC-87-4
Task Number(s):
MR04101003
Project Number(s):
MR04101
 Subject Terms
Joint Capability Areas:
JCA_5_Command and Control; JCA_5.3_Planning; JCA_6_Net Centric; JCA_1_Force Support; JCA_6.1_Information Transport; JCA_1.4_Force Support; JCA_4.1_Deployment and Distribution; JCA_8.2_Shape; JCA_8_Building Partnerships; JCA_1.4.1_Force Health Protection; JCA_1.3_Human Capital Management; JCA_8.2.1_Partner with Governments and Institutions; JCA_1.2.5_Lessons Learned; JCA_1.3.2_Personnel Management; JCA_1.1.1_Global Force Management; JCA_1.1_Force Management; JCA_4_Logistics; JCA_8.2.5_Strengthen Global Defense Posture
Modernization Areas:
Fully Networked C3
Communities of Interest:
Biomedical
Descriptor(s):
*TRYPTOPHAN, *SLEEP, *PERFORMANCE(HUMAN), SLEEP DEPRIVATION, HUMANS, JET LAG, REACTION TIME, DIET, PRECURSORS, SEROTONIN, INSOMNIA, LOGISTICS, REST, EYE MOVEMENTS, NEUROPHYSIOLOGY, RELAXATION(PHYSIOLOGY), MEMORY(PSYCHOLOGY), BIOLOGICAL RHYTHMS, OPERATIONAL READINESS, MILITARY PERSONNEL, THRESHOLDS(PHYSIOLOGY)
Field(s)/Group(s):
Pharmacology
Keyword(s):
Melatomin, Neurotransmitters, PE61153N, WUDN246547
Report Date:
1987 Mar 10