Clinical Pharmacology Studies. Phase 1.

reportActive / Technical Report | Accession Number: ADA181670 | Open PDF

Abstract:

The scientific work of this year centered around the bioavailability, safety, tolerance, pharmacokinetics and pharmacodynamics of pyridostigmine and the absorption, safety, tolerance and pharmacokinetics of single doses of WR 6026. These two studies were completed successfully and efficiently, and complete details can be found in the draft Task Reports which have been submitted. These drafts are in the process of review and revision by Division of Experimental Therapeutics personnel prior to publication of final Task Reports.

Author(s):
Lietman, Paul S. ; Petty, Brent G. ; Kornhauser, David M.
Author Organization(s):
JOHNS HOPKINS UNIV BALTIMORE MD DIV OF CLINICAL PHARMACOLOGY
Descriptive Note:
Annual rept. 1 Jun 85-31 Dec 86,
Pagination:
0018

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release

RECORD

Collection: TR
Identifying Numbers
Contract/Grant Number(s):
DAMD17-85-C-5133
Task Number(s):
AE
Project Number(s):
3M463751D993
 Subject Terms
Joint Capability Areas:
JCA_5_Command and Control; JCA_5.5.2_Task; JCA_5.5_Direct; JCA_6_Net Centric; JCA_6.1_Information Transport; JCA_6.2.3_Core Enterprise Services; JCA_1_Force Support; JCA_1.2_Force Preparation; JCA_5.3_Planning; JCA_6.2_Enterprise Services; JCA_1.2.3_Educating; JCA_6.4.1_Secure Information Exchange; JCA_8.2_Shape; JCA_8_Building Partnerships; JCA_1.2.5_Lessons Learned; JCA_1.3_Human Capital Management
Communities of Interest:
Biomedical
Descriptor(s):
*CLINICAL MEDICINE, *PHARMACOLOGY, *CHOLINESTERASE INHIBITORS, *ANTIPARASITIC DRUGS, ABSORPTION, PHARMACOKINETICS, PERSONNEL, THERAPY, DOSAGE, ANTIDOTES, DRUGS, TOLERANCES(PHYSIOLOGY), SAFETY, BIOLOGICAL ABSORPTION, LEISHMANIASIS, ORGANOPHOSPHATES, POISONING, ACETYLCHOLINESTERASE
Field(s)/Group(s):
Pharmacology
Keyword(s):
*Pyridostigmine, WR 6026 Chemotherapeutic Agents, Antileishmanial drugs, AS993, PE63751A, WU165
Report Date:
1987 Apr 15