Primary Eye Irritation Potential of the Holston Compounds: Virgin DMSO (Dimethyl Sulfoxide), DMSO Recycle Solvent, and DMSO Evaporator Sludge.

reportActive / Technical Report | Accession Number: ADA132407 | Open PDF

Abstract:

The primary eye irritation potential of the Holston Compounds Virgin DMSO, DMSO Recycle Solvent, and DMSO Evaporator Sludge was tested by placing these materials in the conjunctival cul-de-sac of rabbit eyes. The study was conducted in compliance with the Good Laboratory Practice Regulations. All of the Dimethly Sulfoxide compounds tested produced irritation of the conjunctiva early in the study, but the level of severity did not meet the criteria for positive eye irritants.

Author(s):
Kellner, Thomas P. ; White, Craig W. ; Fruin, John T.
Author Organization(s):
LETTERMAN ARMY INST OF RESEARCH PRESIDIO OF SAN FRANCISCO CA
Descriptive Note:
Final rept. 10 Feb-30 Mar 83,
Pagination:
0038

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release

RECORD

Collection: TR
Identifying Numbers
Report Number(s):
LAIR-155, TOXICOLOGY SER-59
 Subject Terms
Joint Capability Areas:
JCA_5_Command and Control; JCA_5.3_Planning; JCA_7.1.2_Prevent Non-kinetic Attack; JCA_7.1_Prevent; JCA_7_Protection; JCA_5.2_Understand; JCA_5.3.3_Develop Strategy; JCA_5.3.4_Develop Courses of Action; JCA_5.3.5_Analyze Courses of Action; JCA_5.5_Direct; JCA_5.5.1_Communicate Intent and Guidance; JCA_6_Net Centric; JCA_3.2_Engagement; JCA_3_Force Application; JCA_4.6_Engineering; JCA_4.7.2_Installation Services; JCA_4.7_Base and Installations Support; JCA_3.2.1_Kinetic Means; JCA_4.6.1_General Engineering; JCA_6.4.1_Secure Information Exchange; JCA_1.4.1_Force Health Protection
Communities of Interest:
No COI(s) Identified
Descriptor(s):
*Methyl sulfoxide, *Toxicity, Physiological effects, Eye, Irritation, Rabbits
Field(s)/Group(s):
Toxicology
Keyword(s):
Holston compounds
Report Date:
1983 Aug 01