Apparent Cytotoxicity of Base Metal Casting Alloys.

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Abstract:

The cytotoxic potentials of three Ni-Cr based alloys Ticonium 100, Gemini II and Victory and an Fe-Cr based alloy Dentillium CB were assessed. In tissue culture, castings of all four test materials and powders of Dentillium CB did not licit adverse cellular changes. However, cultures containing Ni-Cr powders showed prominent zones of lysis and cell alteration. Responses to Victory were more severe than those to Ticonium 100 and Gemini II. The cytotoxic potential of products obtained from the surfaces of casting alloys may offer an expedient means for estimation of long term clinical toxicity. Author

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