Use of Physostigmine by the Intravenous, Intramuscular, and Oral Routes in the Therapy of Anticholinergic Drug Intoxication

Sidell, Frederick R.

Use of Physostigmine by the Intravenous, Intramuscular, and Oral Routes in the Therapy of Anticholinergic Drug Intoxication

Active / Technical Report | Accession Number: ADA025362 |

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Abstract:

Physostigmine was administered by three routes intravenous, intramuscular, and oral to treat intoxication by anticholinergic compounds in man. The drug by all routes of administration is effective. There are several reasons why the intravenous route of administration is not preferable for routine use.

Author(s):

Sidell, Frederick R.

Author Organization(s):

EDGEWOOD ARSENAL ABERDEEN PROVING GROUND MD

Descriptive Note:

Technical rept. Jul 1968-May 1975

Supplementary Note:

DOI: 10.21236/ADA025362

Pagination:

0025

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:

Approved For Public Release

Distribution Statement:

Approved For Public Release; Distribution Is Unlimited.

RECORD

Collection: TR

Identifying Numbers

Report Number(s):

EB-TR-76012

Task Number(s):

1W762710AD2503

Project Number(s):

DA-1-W-762710-AD-25

Monitor Series:

EA

Subject Terms

Joint Capability Areas:

JCA_5_Command and Control; JCA_1.4_Force Support; JCA_5.2_Understand; JCA_1.4.2_Health Service Delivery; JCA_3.2_Engagement; JCA_3_Force Application; JCA_1.4.1_Force Health Protection; JCA_3.2.1_Kinetic Means; JCA_6_Net Centric; JCA_1_Force Support; JCA_6.4.1_Secure Information Exchange; JCA_1.2_Force Preparation; JCA_3.2.2_Non-Kinetic Means; JCA_6.1_Information Transport; JCA_6.4_Information Assurance

Communities of Interest:

Biomedical

Descriptor(s):

*ANTIDOTES, *BELLADONNA ALKALOIDS, ATROPINE, ENLISTED PERSONNEL, HEART, PREVENTION, SCOPOLAMINE, THERAPY, TOXICITY

Field(s)/Group(s):

Toxicology, Pharmacology

Keyword(s):

PHYSOSTIGMINE, BENZILATE 3 QUINUCLIDINYL, ANTICHOLINERGIC AGENTS

Report Date:

1976 May 01