Hazard Evaluation of Candidate Face Net Impregnant ENT-4203-Gd, Isobutyl Mandelate (Rutgers 850).

Weeks, Maurice H.; Pope, Conrad R.

Hazard Evaluation of Candidate Face Net Impregnant ENT-4203-Gd, Isobutyl Mandelate (Rutgers 850).

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Abstract:

A hazard evaluation of the candidate face net impregnant ENT-4203-Gd, isobutyl mandelate Rutgers 850, was performed by means of laboratory animal studies using rats and rabbits. The technical grade compound did not produce primary irritation when applied to the intact or abraded skin of rabbits. Sight injury to the cornea and the conjunctiva were observed after a single application of the technical grade compound to the eyes of rabbits. Data indicate little acute toxic hazard from accidental ingestion. Acute and subchronic aerosol inhalation exposures of rats resulted experimentally in no deleterious effect. It is recommended that ENT-4203-Gd be approved for testing as a candidate face net impregnant.

Author(s):

Weeks, Maurice H. ; Pope, Conrad R.

Author Organization(s):

ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

Descriptive Note:

Final rept. May 71-Aug 74,

Pagination:

0018

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:

Approved For Public Release

RECORD

Collection: TR

Identifying Numbers

Report Number(s):

USAEHA-51-130-71/75

Subject Terms

Communities of Interest:

No COI(s) Identified

Descriptor(s):

*TOXICITY, *INSECT REPELLENTS, *IRRITATING AGENTS, RATS, EYE, SKIN(ANATOMY), BIOASSAY, RABBITS, NETS, LABORATORY ANIMALS, INHALATION, IMPREGNATION, INGESTION(PHYSIOLOGY)

Field(s)/Group(s):

Toxicology

Keyword(s):

*Mandelic acid (isobutyl ester), Recommendations, Evaluation

Report Date:

1975 Mar 28