Market Potential for Perfluorocarbon Based Formulations for Use in Pressurized Metered Dosed Inhalers for Pulmonary Drug Delivery

reportActive / Technical Report | Accession Number: AD1112835 | Open PDF

Abstract:

The overarching goal of the SEMPer Fi saving lives with emergency medical perfluorcarbons program is to develop and commercialize aerosolized therapeutic formulations, based on perfluorocarbon PFC chemistry. Advanced development of these formulations are meant to bridge a technology gap that will allow pharmaceutical hydrophilic compounds to be delivered directly to the lungs via a pressurized metered dose inhaler pMDI. For the military this technology will provide a faster and more efficacious means to target the Hypoxic Pulmonary Vasoconstrictive HPV response, which hinders physical and mental performance of military personnel working in hypoxic environments.

Author(s):
Meyers, Arlen D. ; Pak, David I. ; Irwin, David C. ; Schroeder, Thies D.
Author Organization(s):
University of Colorado - Health Science Center Aurora United States
Descriptive Note:
Technical Report,28 Sep 2017,30 Jun 2019
Pagination:
0013

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release
Distribution Statement:
Approved For Public Release;

RECORD

Collection: TR
Identifying Numbers
Report Number(s):
ARO-72315-SD-ICR.1
Monitor Series:
ARO-72315-SD-ICR.1
 Subject Terms
Joint Capability Areas:
JCA_1.4_Force Support; JCA_1.4.1_Force Health Protection; JCA_7_Protection; JCA_1.4.2_Health Service Delivery; JCA_7.2.1_Mitigate Lethal Effects; JCA_7.2_Mitigate; JCA_1_Force Support; JCA_1.2_Force Preparation; JCA_5_Command and Control; JCA_5.3_Planning; JCA_1.2.3_Educating; JCA_3.2_Engagement; JCA_3_Force Application; JCA_6_Net Centric; JCA_7.1.2_Prevent Non-kinetic Attack; JCA_7.1_Prevent; JCA_5.4_Decide; JCA_6.2.3_Core Enterprise Services; JCA_8_Building Partnerships; JCA_1.2.6_Concepts; JCA_8.2_Shape
Modernization Areas:
Microelectronics
Communities of Interest:
Biomedical
Descriptor(s):
cerebral hypoxia, nebulizers and vaporizers, altitude, health care, lung diseases, therapy, pulmonary hypertension, fibrosis
Field(s)/Group(s):
Medicine and Medical Research
Keyword(s):
pfc(perfluorcarbons), pmdi(pressurized metered dose inhaler), hpv(Hypoxic Pulmonary Vasoconstrictive), business model, commercialization
Report Date:
2020 Apr 24
Creation Date:
2020 Oct 28