Detection of Early Lung Cancer among Military Personnel (DECAMP)

reportActive / Technical Report | Accession Number: AD1094571 | Open PDF

Abstract:

The purpose of this work is to develop and validate molecular biomarkers found in blood, tissues, or other bodily fluids, which may be used for the early detection of lung cancer among military personnel and veterans. Over the course of the last year of this award, we have made significant progress towards enrollment in both clinical trials. We have recruited tilde92 percent of the 500 total subjects in the indeterminate pulmonary nodule study Protocol 1, and tilde69 percent of the 800 total subjects in the longitudinal screening study Protocol 2. The Leadership, Steering, Adjudication, Biostatistics, Imaging and Biomarker Committees continue to meet regularly. Most notably, significant progress has been made in collection and profiling of biospecimens from both cohorts, which will facilitate the validation of our cancer biomarkers. We have secured additional funding for the DECAMP consortium through July 2022, to ensure the completion of our enrollment goals and study aims. Lastly, we are finalizing discussions regarding dissemination and sharing of DECAMP data in the coming years.

Author(s):
Spira, Avrum E. ; Billatos, Ehab ; Moses, Elizabeth
Author Organization(s):
Boston University Boston United States
Descriptive Note:
Technical Report,30 Sep 2011,29 Mar 2019
Pagination:
0025

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release
Distribution Statement:
Approved For Public Release;

RECORD

Collection: TR
Subject Terms
Joint Capability Areas:
JCA_5_Command and Control; JCA_5.3_Planning; JCA_5.3.3_Develop Strategy; JCA_1.2.3_Educating; JCA_2.1_Planning and Direction; JCA_2.1.2_Develop Strategies; JCA_1.3.2_Personnel Management; JCA_7.2.1_Mitigate Lethal Effects; JCA_7.2_Mitigate; JCA_7_Protection; JCA_5.5.2_Task; JCA_5.5_Direct; JCA_1.2.5_Lessons Learned
Communities of Interest:
No COI(s) Identified
Descriptor(s):
health services, medical personnel, military personnel, military medicine, biostatistics, health care, lung cancer, lung diseases, diseases and disorders, gene expression, proteins, biorepositories, biospecimens, blood, cancer, clinical trials, hospitals
Field(s)/Group(s):
Medicine and Medical Research, Anatomy and Physiology
Keyword(s):
decamp(Detection of Early Lung Cancer among Military Personnel)
Report Date:
2019 Jun 01
Creation Date:
2020 Apr 01