A Novel Nutraceutical Drug for OA Treatment

reportActive / Technical Report | Accession Number: AD1089983 | Open PDF

Abstract:

Over 27 million Americans are currently diagnosed with osteoarthritis OA, and OA is our nations leading cause of pain and disability. Medically linked retirement caused by musculoskeletal disorders such as OA increased nearly 10-fold among active military service members between 2003 to 2009. The rate of OA in military populations is twice as high as that in non-military populations. Neither a disease-modifying OA drug nor a non-surgical cure presently exists. Therefore, it is extremely important to have a drug which mitigates OA disease progression and relieves OA pain, with minimal, if any, adverse effects. The aim of the current project is to determine the therapeutic efficacy of a novel botanical drug using a canine model of post-traumatic OA, a large animal model that replicates the pathology and symptoms of human OA. Successful completion of the proposed studies will provide critical evidence to the Food and Drug Administration for approval for human clinical trials.

Author(s):
Sun, Hui B.
Author Organization(s):
Albert Einstein College of Medicine New York United States
Descriptive Note:
Technical Report,30 Sep 2018,29 Sep 2019
Pagination:
0006

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release
Distribution Statement:
Approved For Public Release;

RECORD

Collection: TR
Subject Terms
Joint Capability Areas:
JCA_5_Command and Control; JCA_1_Force Support; JCA_5.3_Planning; JCA_1.2_Force Preparation; JCA_3.2_Engagement; JCA_3_Force Application; JCA_6.4.1_Secure Information Exchange; JCA_1.4.1_Force Health Protection; JCA_1.4_Force Support; JCA_3.2.1_Kinetic Means; JCA_6.4_Information Assurance; JCA_6_Net Centric; JCA_8_Building Partnerships
Communities of Interest:
No COI(s) Identified
Descriptor(s):
musculoskeletal abnormalities, musculoskeletal diseases, joint diseases, therapy, arthritis, clinical trials, disease attributes, abnormalities, pain, diseases and disorders, active duty, military personnel
Field(s)/Group(s):
Medicine and Medical Research
Keyword(s):
Post traumatic osteoarthritis, botanical drug, canine osteoarthritis, gait analysis, disease modifying drug, osteoarthritis pain
Report Date:
2019 Oct 01
Creation Date:
2020 Jan 23