Comparison of Dense Polytetrafluoroethylene (PTFE) and Amniotic Tissue Membranes with Modern Ridge Preservation Techniques on Human Alveolar Ridge Preservation

This single-blind, randomized clinical trial compared two different, commercially available membrane materials to assess their efficacies in socket preservation procedures in 24 patients. This study sought to compare the materials as part of routine, clinicalperiodontal therapy in order to determine superiority. Patients were seen at baseline, then 1, 2, 4 weeks, and 4 months post-treatment. Patients were distributed equally into the following groups Cytoplast CO, Cytoplast with additional buccal augmentation graft, CBA, BioXclude Bx, and BioXclude with additional buccal augmentation graft. BxBA. Cone beam computed tomography CBCT scans were compared between a pre-operative baseline time point and a scan taken four months after healing. The percent of alveolar horizontal and vertical ridge change was measured utilizing subtraction radiology and Dolphin 3D software. Secondary outcomes included ease of use, perceptions of pain, complications, cost-effectiveness, and changes in keratinized tissue. Due to the relatively small sample size attained at an early point of this long-term study, no conclusions with statistical support could be drawn regarding a direct comparison between materials. However, both materials showed loss at all measurement points. There seemed to be no difference in pain scores between the two materials. The continuation of this study may offer some statistical and clinical significance once the population needed is met.