COMBAT - A Prospective, Randomized Investigation of Plasma First Resuscitation for Traumatic Hemorrhage and Attenuation of Acute Coagulopathy of Trauma

The COMBAT Control of Major Bleeding After Trauma study is a randomized clinical trial evaluating the early administration of plasma, compared to the standard crystalloid. Over the past year, we have worked on refining our procedures and workflows, collecting accurate and timely data, ensuring regulatory compliance, and communicating with all study team personnel at Denver Health and the University of Colorado Anschutz Medical Campus. We enrolled a total of 50 patients and collected over 6,000 samples this reporting year in addition to submitting one annual continuing review and publishing several papers.