Response of Rabbits Challenged with Aerosols of Venezuelan Equine Encephalomyelitis Virus.

Garner, William H., Jr.; Tonik, Ellis J.; Jemski, Joseph V.

Response of Rabbits Challenged with Aerosols of Venezuelan Equine Encephalomyelitis Virus.

Active / Technical Report | Accession Number: AD0876588 |

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Abstract:

The ability of aerosols of the Trinidad strain of Venezuelan equine encephalomyelitis virus to induce clinical and lethal responses in New Zealand White rabbits was demonstrated. With few exceptions, the majority of rabbit deaths occurred on days 3 and 4 after challenge from inhaled doses calculated to range from 3 to 22,000 MICLD50, and animal mortalities were predictable on the basis of elevated temperatures, depressed white blood cell counts, and or viremia. Author

Author(s):

Garner, William H., Jr. ; Tonik, Ellis J. ; Jemski, Joseph V.

Author Organization(s):

FORT DETRICK FREDERICK MD

Descriptive Note:

Technical memo.,

Pagination:

0016

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:

Approved For Public Release

RECORD

Collection: TR

Identifying Numbers

Report Number(s):

SMUFD-TM-217, AMXFD-AE-T-49887

Task Number(s):

1B662706A07203

Project Number(s):

DA-1-B-662706-A-072

Subject Terms

Joint Capability Areas:

JCA_3.2_Engagement; JCA_3_Force Application

Communities of Interest:

No COI(s) Identified

Descriptor(s):

*VENEZUELAN EQUINE ENCEPHALOMYELITIS VIRUS, RABBITS, INFECTIOUS DISEASES, VIRUSES, ARBOVIRUSES, LABORATORY ANIMALS, LETHAL DOSAGE, PATHOLOGY, RESPIRATION, MORTALITY RATE

Field(s)/Group(s):

Microbiology

Report Date:

1970 Oct 01