Interactions Between Pathogenic Viral Types and their Host Cells

This report states that virus types which contain the same type of nucleic acid can themselves be synthesized in the host cell and can affect its metabolism in many different ways. Whereas in KP-virus the synthesis of virus- RNA occurs in the cell nucleus, in ME-virus as well as in NDV, which in several respects resembles KP-virus, synthesis apparently occurs in the cytoplasm. Also, whereas there is an immediate, drastic, reduction of normal RNA- and protein- metabolism with ME-virus, these are disturbed relatively little in the most important phase of the proliferation cycle in both myxoviruses.