APPLICATION OF THE IMMUNOFLUORESCENCE TECHNIQUE IN VIROLOGY AND ANATOMOPATHOLOGY,

The immunofluorescence technique was applied in the search for the viral antigen in tumors of the rat caused by the SE poliomyelitis virus and also in the tissue cultures of these tumors. With the assistance of this technique it was demonstrated that, while no viral antigen is present in the tumors themselves, this antigen is synthesized by the cancer cells in a certain percentage in a test tube culture of these growths. The synthesis of the viral antigen was followed morphologically on the cytologic level. Author