Experimental Study of the Effect of the Dose of a Chemical Substance on the Incidence and Intensity of Contact Allergy,

Alekseeva, O. G.; Barlogova, S. G.; Dueva, L. A.; Zagidullin, Sh. Z.; Raben, A. S.

Experimental Study of the Effect of the Dose of a Chemical Substance on the Incidence and Intensity of Contact Allergy,

Active / Technical Report | Accession Number: AD0785210 |

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Abstract:

A direct relationship exists between the dose of a chemical allergen and the intensity of contact allergy. In a large number of chemical allergens, the threshold of allergizing action is below the threshold of toxic action during absorption through the skin. On this basis when setting permissible standards it is not necessary to consider the specific effect. Certain weak allergens can be active sensitizers even in toxic doses.

Author(s):

Alekseeva, O. G. ; Barlogova, S. G. ; Dueva, L. A. ; Zagidullin, Sh. Z. ; Raben, A. S.

Author Organization(s):

FOREIGN TECHNOLOGY DIV WRIGHT-PATTERSON AFB OHIO

Supplementary Note:

Edited trans. of Gigiena Truda i Professionalnye Zabolevaniya (USSR) n6 p19-23 1970, by Catherine M. Barber.

Annotation:

Experimental Study of the Effect of Dose of a Chemical Substance on the Incidence and Intensity of Contact Allergy--Translation.

Pagination:

0011

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:

Approved For Public Release

RECORD

Collection: TR

Identifying Numbers

Report Number(s):

FTD-HT-23-2085-74

Subject Terms

Communities of Interest:

No COI(s) Identified

Descriptor(s):

*Allergic diseases, *Dermatitis, Antigens, Chemical agents, Dosage, Skin(Anatomy), Toxicity, Thresholds(Physiology), Industrial medicine, Immunology, USSR, Translations

Field(s)/Group(s):

Medicine and Medical Research, Environmental Health and Safety

Keyword(s):

*Allergens, *Contact dermatitis

Report Date:

1974 Aug 21