Effect of Storage on Oxygen Transport in Blood Obtained from Man, Dog and Monkey.

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Abstract:

Red cells obtained from human, monkey and canine subjects were stored in acid-citrate-dextrose ACD over a six week period and periodically tested for mid saturation point P50, pH, adenosine triphosphate ATP and 2,3-diphosphoglycerate DPG levels. In addition, blood obtained from dogs kept chronically anemic and also from those undergoing daily exercise was stored and compared to the other groups. The anemic and exercised groups were found to have higher than normal DPG values, with only the exercise group showing corresponding elevation in P50 levels. The results showed a general decrease in all tested values with storage. Modified author abstract

Author(s):
Shields, Charles E. ; Meixner, David E. ; Bratton, Joseph F. ; Brooks, Daniel E. ; Zegna, Angelo I.
Author Organization(s):
ARMY MEDICAL RESEARCH LAB FORT KNOX KY
Descriptive Note:
Progress rept.,
Pagination:
0014

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release

RECORD

Collection: TR
Identifying Numbers
Report Number(s):
USAMRL-1094
Task Number(s):
3A162110A82100
Project Number(s):
DA-3-A-162110-A-821
 Subject Terms
Communities of Interest:
No COI(s) Identified
Descriptor(s):
*BLOOD PRESERVATION, ERYTHROCYTES, HUMANS, MONKEYS, DOGS, OXYGEN, TRANSPORTABLE, PH FACTOR, ADENOSINE PHOSPHATES, BLOOD DONORS, ANEMIAS, EXERCISE(PHYSIOLOGY)
Field(s)/Group(s):
Anatomy and Physiology, Medical Facilities, Equipment and Supplies
Keyword(s):
*Oxygen transport mechanisms, Acid citrate dextrose, Blood preservatives
Report Date:
1974 Apr 16