Virus-Host Interactions in Abnormal Cells.

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Abstract:

Results of the investigation indicated that the infectivity titer of mouse hepatitis virus decreased after 6 hr incubation at 37C. Nutrient fluids from infected macrophage cultures retained pathogenicity in vivo and the ability to form polykaryons in vitro. Electron microscope studies of polykaryons formed from infected macrophage cultures showed the presence of virus-like particles in the cytoplasm. From the study, it was concluded that polykaryon formation in infected macrophage cultures resulted from an active viral agent. Author

Author(s):
Starr, Theodore J.
Author Organization(s):
STATE UNIV COLL BROCKPORT N Y DEPT OF BIOLOGICAL SCIENCES
Descriptive Note:
Technical rept.,
Pagination:
0013

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release

RECORD

Collection: TR
Identifying Numbers
Report Number(s):
TR-1
Contract/Grant Number(s):
N00014-71-C-0237
Project Number(s):
NR-136-827
 Subject Terms
Joint Capability Areas:
JCA_3.2_Engagement; JCA_3_Force Application; JCA_3.2.2_Non-Kinetic Means; JCA_6.4_Information Assurance; JCA_6_Net Centric; JCA_8.1.1_Inform Domestic and Foreign Audiences; JCA_8.1_Communicate; JCA_8_Building Partnerships
Communities of Interest:
No COI(s) Identified
Descriptor(s):
*HEPATITIS VIRUSES, *TISSUE CULTURE CELLS, PHAGOCYTES, CELLS(BIOLOGY), PATHOLOGY, VIRUSES, GROWTH(GENERAL), NUCLEI(BIOLOGY), CHROMOSOMES
Field(s)/Group(s):
Microbiology
Keyword(s):
*POLYKARYOCYTES, CYTOPATHOLOGY
Report Date:
1971 Dec 06