Effect of Varying Concentrations of Adenine, Inosine and Methylene Blue on the Useful Storage Life of Blood.

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Abstract:

The addition of methylene blue in a concentration of .000006M to CPD blood and the simultaneous addition of varying concentrations of adenine or inosine was investigated by determining the levels of ATP, 2,3-DPG and hemoglobin function during storage of whole blood under blood banking conditions for 6 weeks. The results obtained show that the optimum concentration of inosine results in very high levels of 2,3-DPG and of hemoglobin function after 6 weeks of storage when compared to the controls. However, the levels of A

Author(s):
Kocholaty, Walter F. ; Dawson, R. Ben, Jr. ; Billings, Thomas A. ; Ledford, M. Edith ; Gray, John L.
Author Organization(s):
ARMY MEDICAL RESEARCH LAB FORT KNOX KY
Descriptive Note:
Interim rept.,
Pagination:
0015

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release

RECORD

Collection: TR
Identifying Numbers
Report Number(s):
USAMRL-940
Task Number(s):
3A062110A82100
Project Number(s):
DA-3-A-062110-A-821
 Subject Terms
Communities of Interest:
No COI(s) Identified
Descriptor(s):
*ADENINE, *METHYLENE BLUE, *NUCLEOSIDES, STORAGE, BLOOD, BLOOD, BLOOD, PRESERVATION, HEMOGLOBIN, VIABILITY, BLOOD TRANSFUSION
Field(s)/Group(s):
Medical Facilities, Equipment and Supplies
Keyword(s):
*BLOOD PRESERVATIVES, BLOOD BANKS, INOSINES
Report Date:
1971 Jul 19