Sickledex Test for S Hemoglobin: A Critique.

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Abstract:

When the reagents, reactions, and principles of the Sickledex test are understood in terms of modern molecular biology, it is believed that the Sickledex test can be an invaluable and productive tool in the discovery not only of hemoglobin S but other hemoglobinopathies as well, provided 1 certain pitfalls of false positive and false negative reactions are recognized 2 urea is used to modify the test and 3 all positive Sickledex specimens are subsequently studied by hemoglobin electrophoresis technique. Author

Author(s):
Nalbandian, Robert M. ; Henry, Raymond L. ; Lusher, Jeanne M. ; Camp, Frank R., Jr. ; Conte, Nicholas F.
Author Organization(s):
ARMY MEDICAL RESEARCH LAB FORT KNOX KY
Descriptive Note:
Progress rept.,
Pagination:
0009

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release

RECORD

Collection: TR
Identifying Numbers
Report Number(s):
USAMRL-945
Task Number(s):
3A062110A82100
Project Number(s):
DA-3-A-062110-A-821
 Subject Terms
Communities of Interest:
No COI(s) Identified
Descriptor(s):
*ANEMIAS, *HEMOGLOBIN, *BLOOD DISEASES, DETECTION, TEST METHODS, TEST METHODS, UREA, EFFICIENCY, DIAGNOSIS(GENERAL)
Field(s)/Group(s):
Medicine and Medical Research
Keyword(s):
*SICKLE CELL ANEMIA
Report Date:
1971 Aug 04