METABOLIC RESPONSE TO ACCELERATION IN MAN

reportActive / Technical Report | Accession Number: AD0712614 | Open PDF

Abstract:

The glucose analogue 2-deoxy-D-glucose 2-DG was used as a means of producing intracellular hypoglycemia in eight normal male volunteer subjects during a control period, immediately following their initial exposure to acceleration acute acceleration and following their initial exposure to acceleration acute acceleration and following a fourth acceleration exposure chronic acceleration. Plasma glucose, free fatty acids, serum immunoreactive growth hormone, plasma cortisol, and urinary epinephrine and norepinephrine were measured prior to and following the infusions of 2-DG. There were significant depressions in glucose, urinary epinephrine, cortisol and free fatty acids following acceleration that were not seen when compared to basal, unprovoked levels. Even with the modest acceleration stresses used in this study, discernible changes in gluco-regulatory hormone reserves were uncovered.

Author(s):
Lipman, Richard L. ; Ulvedal, Frode ; Brown, William K. ; Leverett, S. D. ; Lecocq, Frank R.
Author Organization(s):
SCHOOL OF AEROSPACE MEDICINE BROOKS AFB TX
Supplementary Note:
Published in Aerospace Medicine, v41 n8 p905-908 Aug 1970.
Pagination:
0006

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release
Distribution Statement:
Approved For Public Release; Distribution Is Unlimited.

RECORD

Collection: TR
Identifying Numbers
Report Number(s):
SAM-TR-70-254
Task Number(s):
793002
Project Number(s):
AF-7930
Monitor Series:
SAM-AF-BR
 Subject Terms
Joint Capability Areas:
JCA_8.2.4_Leverage Capacities and Capabilities of Security Establishments; JCA_8.2_Shape; JCA_8_Building Partnerships; JCA_5_Command and Control; JCA_5.3_Planning
Communities of Interest:
Biomedical
Descriptor(s):
*METABOLISM, ACCELERATION TOLERANCE, BIOCHEMISTRY, BLOOD CHEMISTRY, BLOOD PLASMA, CORTICOSTEROID AGENTS, EPINEPHRINE, FATTY ACIDS, FLIGHT, GLUCOSE, HORMONES, HYPOGLYCEMIA, SPACE FLIGHT, STRESS(PHYSIOLOGY)
Field(s)/Group(s):
Biochemistry, Stress Physiology
Keyword(s):
LEVARTERENOL, *ACCELERATION TOLERANCE, *STRESSES, REPRINTS
Report Date:
1970 Mar 01