A MATHEMATICAL MODEL OF PLACENTAL OXYGEN TRANSFER,

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Abstract:

A mathematical model of placental oxygen transfer is used to argue that the experimentally observed control of fetal oxygen concentration in fetal lambs can be explained by the nature of oxyhemoglobin dissociation functions and the differences between these functions in fetal and maternal blood. It is not essential to the explanation to posit any mechanisms responding to a pO2 sensor or any changes in fetal, maternal, or placental vascular structures. Equally unnecessary are assumed alterations in the physical or chemical structure of placental membranes. Aurthor

Author(s):
Kirschbaum, T. H. ; Shapiro, N. Z.
Author Organization(s):
RAND CORP SANTA MONICA CALIF
Pagination:
0052

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release

RECORD

Collection: TR
Identifying Numbers
Report Number(s):
RM-5262-PR
Contract/Grant Number(s):
F44620-67-C-0045
 Subject Terms
Communities of Interest:
No COI(s) Identified
Descriptor(s):
(*RESPIRATION, MATHEMATICAL MODELS), (*EMBRYOS, RESPIRATION), PLACENTA, OXYGEN, BLOOD CHEMISTRY, PHYSIOLOGY, BLOOD VESSELS, MAMMALS
Field(s)/Group(s):
Anatomy and Physiology
Report Date:
1969 Aug 01