METABOLIC EFFECTS OF BLOOD TRANSFUSION.

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Abstract:

The metabolic effects of massive blood transfusion have been studied. The effects of citrate-induced hypocalcemia, elevated potassium concentrations, and metabolic acidosis have been examined individually and in combination in the experimental dog and in the isolated guinea pig atrium. Special attention has been given to the role of adrenergic mechanisms in circulatory homeostasis during massive transfusion. Chemical, electrocardiographic, and hemodynamic methods have been developed to allow on-line investigation of the special risks and ultimate routine monitoring of the circulation during massive transfusion. Author

Author(s):
Bunker, John P.
Author Organization(s):
STANFORD UNIV CALIF
Descriptive Note:
Final rept. 1 Sep 60-29 Feb 68,
Pagination:
0010

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release

RECORD

Collection: TR
Identifying Numbers
Contract/Grant Number(s):
DA-49-193-MD-2135
 Subject Terms
Communities of Interest:
No COI(s) Identified
Descriptor(s):
(*BLOOD TRANSFUSION, *METABOLISM), METABOLIC DISEASES, BLOOD, CITRATES, CALCIUM, POTASSIUM, ACIDOSIS, CITRIC ACID, ADRENAL GLANDS
Field(s)/Group(s):
Anatomy and Physiology
Report Date:
1969 Aug 01