STUDIES OF BOTULINUM ANTIGENS AND ANTISERA BY ZONE ELECTROPHORESIS AND AGAR GEL DIFFUSION

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Abstract:

Studies show that the production of type A botulinum toxins in cellophane sacs is practicable, economical and of great practical importance. The method of fractionation by paper electrophoresis, preparative electrophoresis, immuno-electrophoresis and precipitation by diffusion in agar applied to a study of the fractions and antigenic structure of toxins, toxoids and antitoxins, and also to establish the role of each separate fraction, will be of assistance in establishing the requirements which preparations of the highest quality should comply with, and in devising the most rational method for the purification and concentration of antigens and antibodies.

Author(s):
Gendon, Yu. Z.
Author Organization(s):
ARMY BIOLOGICAL LABS FREDERICK MD
Supplementary Note:
Trans. of Zhurnal Mikrobiologii, Epidemiologii i Immunobiologii (USSR) v29 n2 p95-100 1958.
Annotation:
Studies of botulinum antigens and antisera by zone electrophoresis and agar gel diffusion--Translation.
Pagination:
0006

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release, Document Partially Illegible
Distribution Statement:
Availability: Document Partially Illegible.

RECORD

Collection: TR
Identifying Numbers
Report Number(s):
TRANS-2294
Monitor Series:
ABL/MD
 Subject Terms
Joint Capability Areas:
JCA_1.2.7_Experimentation; JCA_8.1.1_Inform Domestic and Foreign Audiences; JCA_8.1_Communicate; JCA_8_Building Partnerships
Communities of Interest:
No COI(s) Identified
Descriptor(s):
*CLOSTRIDIUM BOTULINUM, USSR, PURIFICATION, TRANSLATIONS, DIFFUSION, IMMUNE SERUMS, IMMUNITY, PH FACTOR, ELECTROPHORESIS, TOXINS AND ANTITOXINS, VACCINES, GLOBULINS, GROWTH(PHYSIOLOGY), CULTURE MEDIA
Field(s)/Group(s):
Microbiology
Keyword(s):
*ANTIGENS, ANTIBODIES, FOREIGN REPORTS
Report Date:
1958 Jan 01