THE TREATMENT OF ACUTE RESPIRATORY FAILURE IN EXPERIMENTAL FAT EMBOLISM

reportActive / Technical Report | Accession Number: AD0678595 | Open PDF

Abstract:

This work was undertaken to investigate effectiveness of various therapeutic trials in experimental and clinical respiratory distress. Using an experimental model of fat embolism, continuous positive pressure breathing, intermittent positive pressure breathing, oxygen, and corticosteroid have been evaluated. Continuous positive pressure breathing has provided better oxygenation at lower minute ventilation than intermittent positive pressure breathing. The use of oxygen does not appear to be beneficial in these experimental animals. Corticosteroids have been valuable in the treatment of clinical fat embolism but have not improved results in experimental animals.

Author(s):
Ashbaugh, David G.
Author Organization(s):
COLORADO UNIV MEDICAL CENTER DENVER DENVER
Descriptive Note:
Technical Report,01 Feb 1968,15 Nov 1968
Pagination:
0026

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release
Distribution Statement:
Approved For Public Release;

RECORD

Collection: TR
Identifying Numbers
Report Number(s):
1
Contract/Grant Number(s):
DADA17-68-C-8078
 Subject Terms
Joint Capability Areas:
JCA_1.4_Force Support; JCA_1.4.1_Force Health Protection; JCA_1.2.7_Experimentation; JCA_5_Command and Control; JCA_JCA_4.1.2_Sustain the Force; JCA_4.1_Deployment and Distribution
Communities of Interest:
Biomedical
Descriptor(s):
RESPIRATORY tract DISEASES, THERAPY, FATS, LABORATORY ANIMALS, OLEIC ACID, INJECTIONS (MEDICINE), RESPIRATORS, SURVIVAL, HUMANS, HEART, HEMOGLOBIN, CORRELATION TECHNIQUES, DISEASES, WOUNDS AND INJURIES, oxygen
Field(s)/Group(s):
Medicine and Medical Research
Keyword(s):
ACUTE RESPIRATORY FAILURE, EXPERIMENTAL FAT EMBOLISM, SIMULATION, MORTALITY RATE, OXYGEN CONSUMPTION, BLOOD PRESSURE, Continuous Positive Pressure Breathing, Intermittent Positive Pressure Breathing, Corticosteroids, Lung Compliance, Cardiac Index
Report Date:
1968 Nov 15