MECHANISM OF THE PASTEUR EFFECT

reportActive / Technical Report | Accession Number: AD0678143 | Open PDF

Abstract:

When nucleated pigeon erythrocytes are treated with nitrite or hydrogen peroxide the Pasteur effect is lost or greatly diminished the respiration remains unchanged, but aerobic lactic acid formation sets in, attaining the level of anaerobic glycolysis. The effect does not depend on methemoglobin formation in nitrited cells incubation with excess lactate brings about a complete reduction of methemoglobin, but the inhibition of the Pasteur effect persists. The suppression of the Pasteur effect produced by H2O2 was found to be reversible and disappears on subsequent treatment with sodium hydrosulphite, though this has no effect on nitrited cells.

Author(s):
Shapot, V. S.
Author Organization(s):
ARMY BIOLOGICAL LABS FREDERICK MD
Supplementary Note:
Trans. of Biokhimiya (USSR) v10 n1 p45-53 1945. DOI: 10.21236/AD0678143
Annotation:
Mechanism of the Pasteur effect--Translation.
Pagination:
0010

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release, Document Partially Illegible
Distribution Statement:
Approved For Public Release; Distribution Is Unlimited. Document Partially Illegible.

RECORD

Collection: TR
Identifying Numbers
Report Number(s):
TRANS-957
Monitor Series:
SMUFD
 Subject Terms
Joint Capability Areas:
JCA_1.2.7_Experimentation; JCA_5.3_Planning; JCA_5_Command and Control
Modernization Areas:
Autonomy
Communities of Interest:
No COI(s) Identified
Descriptor(s):
*FERMENTATION, USSR, REACTION KINETICS, ENZYMES, HEMOGLOBIN, HYDROGEN PEROXIDE, LACTIC ACID, NITRITES, GLYCOLYSIS, ERYTHROCYTES, INHIBITION, TRANSLATIONS, RESPIRATION
Field(s)/Group(s):
Biochemistry
Keyword(s):
MOLYBDENUM(IV) SULFIDE, FOERIGN REPORTS
Report Date:
1963 Jun 01