FORMATION OF METHYLENE BRIDGES IN THE REACTION OF RIBONUCLEIC ACID WITH FORMALDEHYDE

reportActive / Technical Report | Accession Number: AD0639794 | Open PDF

Abstract:

From RNA, processed with formaldehyde, a product of the condensation of adenosine with formaldehyde was isolated. It was identified by chromatographic mobility and UV spectrum as methylene-bis-adenosine. In the alkaline hydrolyzate of RNA, treated with C14H2O, C14-methylene-bis-adenylic acid was detected chromatographically. Thus, experimental confirmation was obtained of the earlier expressed supposition concerning the formation of methylene bridges in the reaction of RNA with formaldehyde.

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release
Distribution Statement:
Approved For Public Release; Distribution Is Unlimited.

RECORD

Collection: TR
Identifying Numbers
Subject Terms