BIOLOGICAL PROPERTIES OF THE NIIEG TULAREMIA VACCINE STRAINS

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Abstract:

The NIIEG vaccine tularemia strains No. 10, 33 and 53 practically preserved all their biological characteristics in the process of a 10-year storage in a dried state in saccharose-gelatin medium. The NIIEG vaccine strains No. 10 and 53 are harmless for guinea pigs and highly immunogenic in tests on white mice and guinea pigs, but possess an increased residual virulence for white mice in comparison with the standard Gayskiy No. 15 strain. The NIIEG vaccine strains No. 10 and 53, based both on their biological properties disclosed at the present time as well as in a test on their wide application in the past, may be recommended as reserves for the production of live tularemia vaccine. The NIIEG vaccine strain No. 33, based on agglutinability and immunogenic properties, is inferior to the other strains and cannot be recommended for the production of live vaccine.

Author(s):
Sirotyuk, L. V.
Author Organization(s):
ARMY BIOLOGICAL LABS FREDERICK MD
Supplementary Note:
Trans. of Zhurnal Mikrobiologii, Epidemiologii i Immunobiologii (USSR) v41 n10 p116-20, 1964.
Annotation:
BIOLOGICAL PROPERTIES OF THE NIIEG TULAREMIA VACCINE STRAINS -- Translation.
Pagination:
0007

Security Markings

DOCUMENT & CONTEXTUAL SUMMARY

Distribution:
Approved For Public Release
Distribution Statement:
Approved For Public Release; Distribution Is Unlimited.

RECORD

Collection: TR
Identifying Numbers
Report Number(s):
TRANSLATION-1368, ABL/MD-TT-66-60109
Monitor Series:
TT-66-60109, ABL/MD
 Subject Terms
Joint Capability Areas:
JCA_8.1.1_Inform Domestic and Foreign Audiences; JCA_8.1_Communicate; JCA_8_Building Partnerships; JCA_1.4.2_Health Service Delivery; JCA_1.4_Force Support
Communities of Interest:
No COI(s) Identified
Descriptor(s):
*PASTEURELLA, USSR, PRODUCTION, VIABILITY, TRANSLATIONS, STORAGE, MICE, IMMUNITY, VACCINES, GUINEA PIGS, CULTURE MEDIA
Field(s)/Group(s):
Microbiology
Keyword(s):
FOREIGN REPORTS
Report Date:
1965 Jun 01